APIXABAN LIQUID FORMULATIONS Russian patent published in 2018 - IPC A61K9/08 A61K31/437 A61K47/34 A61K47/10 A61K47/36 

Abstract RU 2660358 C2

FIELD: medicine.

SUBSTANCE: invention relates to medicine, in particular, to a liquid medicinal composition of an antithrombotic action containing apixaban and a carrier. Carrier in the liquid composition is a non-ionic surfactant, a hydrophilic polymer, a polyhydric alcohol, polyethylene glycol and an ionic surfactant. Liquid medicinal composition is characterised by the degree of solubility of apixaban in the carrier at least 0.50 mg / ml.

EFFECT: implementation of the invention makes it possible to obtain a liquid composition with a desired concentration of apixaban in the desired dosage and in acceptable volumes that can be accurately measured and conveniently administered.

29 cl, 11 ex, 3 dwg, 10 tbl

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RU 2 660 358 C2

Authors

Badawy Sherif Ibraham Farag

Lum Susan

Dates

2018-07-05Published

2013-09-26Filed