FIELD: medicine.
SUBSTANCE: invention relates to medicine, in particular, to a liquid medicinal composition of an antithrombotic action containing apixaban and a carrier. Carrier in the liquid composition is a non-ionic surfactant, a hydrophilic polymer, a polyhydric alcohol, polyethylene glycol and an ionic surfactant. Liquid medicinal composition is characterised by the degree of solubility of apixaban in the carrier at least 0.50 mg / ml.
EFFECT: implementation of the invention makes it possible to obtain a liquid composition with a desired concentration of apixaban in the desired dosage and in acceptable volumes that can be accurately measured and conveniently administered.
29 cl, 11 ex, 3 dwg, 10 tbl
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Authors
Dates
2018-07-05—Published
2013-09-26—Filed