METHOD FOR DEFINITION OF ABACAVIR Russian patent published in 2018 - IPC G01N33/15 G01N21/33 

FIELD: medicine.

SUBSTANCE: invention relates to the field of medicine and can be used in control and analytical laboratories for standardization and quality control of medicines. Method for determining the mass fraction of abacavir sulfate in the preparation of abacavir sulfate includes spectrophotometry of the substance to be determined and a reference sample, and the calculation of the mass fraction of abacavir taking into account the conversion factor of 0.4194. In this case, 0.1 M sodium hydroxide solution is used as the solvent for preparing the solution to be determined, the concentration of the preparation of abacavir sulfate in the test solution is 0.000010 g/ml, spectrophotometry is carried out at a wavelength of 285 nm, and tropeolin 00 is used as a reference sample.

EFFECT: method makes it possible to increase the reproducibility of abacavir test results and to reduce the analytical error.

1 cl, 3 ex