FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, specifically to blood brain barrier shuttles, which can be used in medicine. In the method, the blood brain barrier shuttle is obtained that binds to the transferrin receptor, contains a specific scFab, linker and effector element for the brain that is used in pharmaceutical compositions for transporting an effector element to the brain through the blood brain barrier.
EFFECT: invention allows the effective use of various therapeutic agents for the treatment of neurodegenerative disorders, preferably Alzheimer's disease.
20 cl, 16 dwg, 2 tbl, 11 ex
| Title | Year | Author | Number |
|---|---|---|---|
| SHUTTLE FOR BLOOD-BRAIN BARRIER | 2013 |
|
RU2711552C2 |
| SHUTTLE FOR BLOOD-BRAIN BARRIER | 2019 |
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|
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|
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|
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|
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|
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RU2731156C1 |
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