FIELD: biotechnology.
SUBSTANCE: invention refers to biotechnology, namely to shuttle for blood-brain barrier. Shuttle contains a full-size IgG-type antibody, a linker and one scFab, the target of which is the transferrin receptor, which is linked to the C-terminus of the Fc-fragment of one of the heavy chains of full-length IgG by means of a linker.
EFFECT: invention widens the range of equipment.
8 cl, 37 dwg, 2 tbl, 11 ex
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