FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, medicine and veterinary medicine. Use of substituted hydrazones of 5-arylfurfurols is proposed selected from CL-192, CL-193, CL-195 or CL-196, given in formula, as intracellular inhibitor of brucellosis infection. Compounds have inhibitory activity against intracellular brucellosis infection and do not show significant cytotoxic activity.
EFFECT: compounds can be used to create alternative antibiotics or combined medicinal and prophylactic means of protection against causative agent of human brucellosis.
1 cl, 4 dwg, 4 ex
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Authors
Dates
2018-08-01—Published
2017-08-21—Filed