METHOD OF PHARMACOLOGICAL PROTECTION FROM IONIZING RADIATION Russian patent published in 2018 - IPC A61K31/155 A61P39/00 

Abstract RU 2663465 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely, to radiology, and can be used for pharmacological protection against ionizing radiation. Method comprises parenteral administration of 1-isobutanoyl-2-isopropyl isothiourea hydrobromide (compound T1023) in a dose of 1/12 to 1/4 LD16 20–60 minutes before the radiation exposure and 10–20 minutes after the radiation exposure, administer 5-methoxytryptamine hydrochloride in a dose of 1/24 to 1/6 LD16.

EFFECT: use of the invention makes it possible to provide high anti-radiation efficacy in the combined use of relatively low, more safe doses of pharmacological components due to their synergistic action.

1 cl, 2 dwg, 7 tbl, 4 ex

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Authors

Filimonova Marina Vladimirovna

Makarchuk Viktoriya Mikhajlovna

Filimonov Aleksandr Sergeevich

Shevchenko Lyudmila Ivanovna

Chesnakova Ekaterina Aleksandrovna

Galkin Vsevolod Nikolaevich

Kaprin Andrej Dmitrievich

Dates

2018-08-06Published

2017-10-05Filed