FIELD: chemistry.
SUBSTANCE: group of inventions includes the novel benzene-sulfonamide derivatives, the claimed compounds pharmaceutical compositions, and the compound of formula (I) use as the oxytocin receptor agonist and their use for the medicinal preparation with the oxytocin receptor agonist activity manufacturing. Technical result: compounds of formula (I) have the good oxytocin receptor affinity
.
EFFECT: group of inventions can find application in the treatment of autism, stress, including post-traumatic stress disorder, anxiety, including anxiety disorders and depression, schizophrenia, mental disorders and memory losses, alcohol abstinence, drug addiction and for the Prader-Willi syndrome treatment.
8 cl, 3 tbl, 26 ex
| Title | Year | Author | Number |
|---|---|---|---|
| PYRIMIDINE DERIVATIVES WITH INHIBITING ACTION WITH RESPECT TO 11b-HSD1 | 2005 |
|
RU2375351C2 |
| DERIVATIVES OF IMIDAZOPYRIDINE STIMULATING NEUROGENESIS | 2013 |
|
RU2644949C2 |
| HETEROCYCLIC ARYL SULPHONES, SUITABLE FOR TREATING DISORDERS RESPONSIVE TO 5HT RECEPTOR MODULATION | 2007 |
|
RU2451012C2 |
| NAPHTHYRIDINE DERIVATIVES | 2006 |
|
RU2418799C2 |
| DERIVATIVES OF (3-METHYLPYRROLIDIN-3-YL)-METHYL PYRIDINYL ETHER AND THEIR USE AS ANTAGONISTS OF RECEPTOR NK-3 | 2011 |
|
RU2625798C2 |
| THIAZOLO[4,5-c]PYRIDINE DERIVATIVES mGluR5 RECEPTOR ANTAGONISTS | 2006 |
|
RU2425834C2 |
| COMT INHIBITORS | 2013 |
|
RU2642779C2 |
| NEW AZACYCLIC COMPOUNDS | 2011 |
|
RU2603263C2 |
| FLUORO-SUBSTITUTED 2-OXO-AZEPANE DERIVATIVES | 2006 |
|
RU2419611C2 |
| PYRIDINE-2-CARBOXAMIDE DERIVATIVES AS mGluR5 ANTAGONISTS | 2006 |
|
RU2411237C2 |
