ISOPROPYL N-[{[(1R)-2-(6-AMINO-9H-PURIN-9-IL)-1-METHYLETOXY]METHYL} (1,3-BENZOTIAZOL-6-IL-OXY)PHOSPHORYL]-L-ALANINATE FUMARAT AS AN ANTIVIRAL DRUG - PRODRUG OF TENOFOVIR Russian patent published in 2018 - IPC C07D471/02 C07F9/6541 

Abstract RU 2665037 C2

FIELD: chemistry.

SUBSTANCE: invention relates to isopropyl N-[{[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl}(1,3-benzothiazol-6-yl-oxy)phosphoryl]-L-alaninate fumarate of formula 1.

EFFECT: compound of the invention has antiviral properties with respect to hepatitis B viruses and is intended for the treatment of viral hepatitis B.

5 cl, 2 tbl, 2 ex

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RU 2 665 037 C2

Authors

Sizyukhin Andrej Vladimirovich

Shafeev Mikhail Ajratovich

Dates

2018-08-27Published

2016-12-12Filed