FIELD: medicine.
SUBSTANCE: present invention relates to aliphatic ester prodrugs of tenofovir, namely to a group of compounds indicated in the claim of the invention that have antiviral activity relatively to HIV-1. A pharmaceutical composition for inhibiting reverse HIV transcriptase is also proposed.
EFFECT: obtaining new compounds suitable for use in the prevention or treatment of HIV infection.
7 cl, 4 tbl, 17 ex
Title | Year | Author | Number |
---|---|---|---|
ADENOSINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 2020 |
|
RU2824528C2 |
4'-SUBSTITUTED NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS AND PRODUCTION THEREOF | 2016 |
|
RU2720811C2 |
PHOSPHORUS(N)AMIDATEACETAL AND PHOSPH(OH)ATACETAL COMPOUNDS | 2019 |
|
RU2796403C2 |
PURINE INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA | 2013 |
|
RU2661896C2 |
PURINE INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA | 2013 |
|
RU2658006C2 |
IMIDAZOQUINOLINE SUBSTITUTED PHOSPHORIC ACID ESTER AS AGONIST, ITS PREPARATION AND USE | 2020 |
|
RU2812182C1 |
BENZOXAZINYL-AMIDOCYCLOPENTYL-HETEROCYCLIC MODULATORS OF CHEMOKINE RECEPTORS | 2004 |
|
RU2301802C2 |
SUBSTITUTED PURINE AND 7-DEAZAPURINE COMPOUNDS | 2011 |
|
RU2606514C2 |
AMINO-DERIVATIVES OF OXO- OR HYDROXY-SUBSTITUTED HYDRAZINES, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITION OF RETROVIRUS PROTEASE | 1993 |
|
RU2126794C1 |
NUCLEOTIDES INCLUDING N-[(S)-1-CYCLOBUTOXYCARBONYL]PHOSPHORAMIDATE FRAGMENT, THEIR ANALOGS AND THEIR APPLICATION | 2017 |
|
RU2659388C1 |
Authors
Dates
2021-11-18—Published
2017-12-20—Filed