FIELD: technological processes.
SUBSTANCE: present invention is directed to the removal of fluoromethyl-1,1,3,3,3-pentafluoroisopropenyl ether (compound A) from sevoflurane in order to obtain high purity sevoflurane. One aspect of the invention relates to a process for the production of sevoflurane substantially free of compound A, comprising the following steps: bringing the composition containing hydrogen fluoride and water at a weight ratio of 1:1 to 1:30 into contact with an organic liquid containing sevoflurane and compound A, to obtain an organic liquid containing compound A in an amount that is less than its amount in the starting organic liquid and distilling the resulting organic liquid in the presence of a degradation inhibitor.
EFFECT: obtaining high purity sevoflurane.
12 cl, 1 dwg, 7 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR WASHING SEVOFLURANE CONTAINER AND METHOD FOR STORING SEVOFLURANE | 2016 |
|
RU2685412C2 |
| METHOD FOR PRODUCING 1,1-DIBROMO-1-FLUOROETHANE | 2014 |
|
RU2670757C2 |
| AZEOTROPIC COMPOSITIONS CONTAINING 2,3,3,3-TETRAFLUOROPROPENE AND HYDROGEN FLUORIDE, AND USE THEREOF IN METHODS OF PRODUCING 2,3,3,3-TETRAFLUOROPROPENE | 2006 |
|
RU2422427C2 |
| TWO-STAGE METHOD OF OBTAINING 2-(FLUOROMETHOXY)-1,1,1,3,3,3-HEXAFLUOROISOPROPANE (SEVOFLURANE) | 2007 |
|
RU2368597C2 |
| NEW ALICYCLE DIOL COMPOUND AND METHOD OF ITS OBTAINMENT | 2013 |
|
RU2646220C2 |
| PERFLUOROCARBOXYLIC ACID SALT AND SYNTHESIS METHOD THEREOF | 2007 |
|
RU2453529C2 |
| METHOD OF PRODUCING ALKOXYLATED ALCOHOL | 2005 |
|
RU2380348C2 |
| METHOD OF PREPARING SUBSTITUTED MONOFLUOROMETHYL ETHERS | 1998 |
|
RU2169724C2 |
| METHOD OF EXTRACTION OF HYDROGEN FLUORIDE | 1998 |
|
RU2194007C2 |
| METHOD FOR PRODUCING HEXAFLUOROISOPROPANOL AND FLUOROMETHYLGEXAFLUOROISOPROPYL ETHER (SEVOFLURANE) | 2016 |
|
RU2629366C2 |
