HYDROGEL FOR CORRECTING THE POST-TREPANATION DEFECT OF THE SKULL Russian patent published in 2018 - IPC A61K31/734 A61K33/00 A61K31/74 A61K31/198 

Abstract RU 2666595 C1

FIELD: medicine.

SUBSTANCE: invention relates to experimental medicine, namely to tissue engineering, and can be used in neurosurgery and traumatology. Hydrogel containing, mass. %: sodium alginate – 5–10; polyvinyl alcohol – 0.5–5; D-asparagine – 0.01–1.0; sodium silicate or potassium silicate – 0.05–1.0; calcium gluconate – 1.0; highly purified water – up to 100 % of the mixture by weight.

EFFECT: preparation allows to obtain a biodegradable skeleton on the 40th day after implantation into the region of the treponation defect of the parietal bone of the rat, in which signs of ingrowth of cellular elements of bone tissue are noted.

1 cl, 1 dwg, 1 ex

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RU 2 666 595 C1

Authors

Kade Azamat Khalidovich

Trofimenko Artem Ivanovich

Zanin Sergej Aleksandrovich

Turovaya Alla Yurevna

Koshelev Igor Grigorevich

Gusejnov Rashid Alkhampashaevich

Chitanava Tamara Vangelevna

Melkikh Natalya Igorevna

Dates

2018-09-11Published

2017-09-26Filed