HUTC MODULATION OF PRO-INFLAMMATORY MEDIATORS OF LUNG AND PULMONARY DISEASES AND DISORDERS Russian patent published in 2018 - IPC A61K35/48 

Abstract RU 2668389 C2

FIELD: medicine.

SUBSTANCE: invention relates to cellular biology and biotechnology, in particular to the use of hUTC cells, a method of reducing and a kit for reducing the production of one or more pro-inflammatory mediators TNF-α, RANTES, IL-1β and combinations thereof in a patient with chronic obstructive pulmonary disease (COPD). Method comprises administering an effective amount of isolated cells derived from human post-natal umbilical cord tissue, essentially free of blood, capable of self-renewal and propagation in culture, not producing CD117 and CD45 and not expressing hTERT or telomerase.

EFFECT: invention enables to reduce production TNF-α, RANTES, IL-1β and combinations thereof in a patient with COPD.

20 cl, 13 dwg, 13 tbl, 13 ex

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RU 2 668 389 C2

Authors

Kikhm Entoni Dzh.

Dates

2018-09-28Published

2013-05-14Filed