FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, specifically to antibodies that specifically bind to hepcidin, which can be used in medicine. Monoclonal antibodies against the peptide of the N-terminal portion of hepcidin are obtained, which are used in the composition and used to treat diseases associated with elevated hepcidin levels or iron homeostasis disorders.
EFFECT: invention makes it possible to obtain therapeutically useful anti-hepcidin antibodies, having a high specificity and a low dissociation constant as compared to the analogues available in the current art.
27 cl, 32 dwg, 10 ex
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Authors
Dates
2018-09-28—Published
2014-03-13—Filed