ANTI-HEPCIDIN ANTIBODIES AND USES THEREOF Russian patent published in 2018 - IPC A61K39/395 C12N15/11 C12N15/63 C12N5/10 A61P3/00 A61P43/00 

Abstract RU 2668391 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology, specifically to antibodies that specifically bind to hepcidin, which can be used in medicine. Monoclonal antibodies against the peptide of the N-terminal portion of hepcidin are obtained, which are used in the composition and used to treat diseases associated with elevated hepcidin levels or iron homeostasis disorders.

EFFECT: invention makes it possible to obtain therapeutically useful anti-hepcidin antibodies, having a high specificity and a low dissociation constant as compared to the analogues available in the current art.

27 cl, 32 dwg, 10 ex

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RU 2 668 391 C2

Authors

Westerman Mark

Ostland Vaughn

Han Huiling

Gutschow Patrick

Westerman Keith

Olbina Gordana

Dates

2018-09-28Published

2014-03-13Filed