METHOD FOR PREDICTING THE RISK OF DEVELOPING ISCHEMIC-CERVICAL INSUFFICIENCY IN SINGLE-PREGNANCY, WHICH RESULTED FROM ASSISTED REPRODUCTIVE TECHNOLOGIES Russian patent published in 2018 - IPC A61B10/00 

FIELD: medicine.

SUBSTANCE: invention relates to obstetrics. Method consists in the fact that during the setting up for a clinical check-up, an anamnesis is collected and the prognostic index D is calculated from the formula D=2.311X1-2.509X2-5.612X3-3.102X4-5.821X5-4.468X6-3.984X7+const, where X1 – factor of infertility: if the patient has a tubal-peritoneal factor of infertility, then X1 = 1, if not, then X1 = 0; X2 – parity: if a patient with a history of obstetrical and gynecological history: medical abortions, regressing pregnancies, miscarriages in the anamnesis and she will have the first birth, then X2 = 1, if the patient is first-bred as a result of ART, then X2 = 0; X3 – the presence of history of ischemic-cervical (IC) insufficiency in the anamnesis: if the patient's previous pregnancies ended with late spontaneous miscarriages or early premature births or in previous pregnancies IC deficiency was detected, then X3 = 1, if not, then X3 = 0; X4 – the presence of gram-negative microflora in the bacteriological study of the lower part of the genital tract: if so, then X4 = 1, if not, then X4 = 0; X5 – an indication of the treated inflammatory diseases of the lower part of the genito-urinary tract caused by the ureaplasma and/or mycoplasma when preparing for the ART protocol: if so, X5 = 1, if not, then X5 = 0; X6 – presence in the patient of chronic diseases of ENT organs: if yes, then X6 = 1, if not, then X6 = 0; X7 – presence in the patient of an anamnesis of chronic inflammatory diseases of the appendages: if yes, then X7 = 1, if not, then X7 = 0; const = +1.906, and if the value of the obtained index D is less than zero, then a high risk of developing an IC of insufficiency is predicted, and if the value of D is greater than or equal to zero, then a conclusion is made about the absence of this risk in a pregnant woman.

EFFECT: method ensures timely detection in pregnant women of the risk group for the formation of IC deficiency, more careful observation and timely correction of this complication of pregnancy to reduce the frequency of late spontaneous miscarriages and early premature births.

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