FIELD: medicine; neonatology; pediatrics; hematology.
SUBSTANCE: invention can be used to predict the development of arterial and venous thrombosis in newborns. Determining the presence of chronic placental insufficiency, fetal growth retardation syndrome, isthmic-cervical insufficiency, male sex, infectious factor, conjugation hyperbilirubinemia, respiratory failure in the neonatal period, carriage of genotype T/T gene polymorphism ITGA2 in position 807 and genotype 4G/4G polymorphism of gene PAI-1 in position −675. Obtained results are evaluated in points and the discriminant function F is calculated. If F is less than 0, a high risk of thrombosis is predicted, and if F is more than 0, there is no risk of developing arterial and venous thrombosis in the newborn in the early and late neonatal period.
EFFECT: method provides high accuracy, sensitivity and specificity of prognosis due to determination of integral value obtained as a result of assessment of anamnestic and clinical-laboratory signs in points.
1 cl, 1 tbl, 2 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD OF PREDICTING DEVELOPMENT OF MULTIFACTOR PATHOLOGY IN CHILDREN BORN WITH APPLICATION OF AUXILIARY REPRODUCTIVE TECHNOLOGIES | 2011 |
|
RU2456911C1 |
METHOD FOR PERICONCEPTIONAL PREDICTION OF RECURRENT EARLY REPRODUCTIVE LOSSES AND PRIMARY PLACENTAL INSUFFICIENCY | 2019 |
|
RU2709246C1 |
METHOD FOR PREDICTION OF INTRAVENTRICULAR HEMORRHAGES IN PREMATURE NEWBORNS | 2020 |
|
RU2741722C1 |
METHOD FOR PREDICTION OF THROMBUS FLOTATION IN INFERIOR VENA CAVA WITH USING MOLECULAR GENETIC MONITORING ADDITIONALLY | 2012 |
|
RU2517215C2 |
METHOD OF PREDICTING DEVELOPMENT OF EARLY NEONATAL SEPSIS IN NEWBORNS WHOSE MOTHERS HAD COVID-19 DURING PREGNANCY | 2023 |
|
RU2813809C1 |
METHOD OF NEUROLOGIC DIAGNOSIS PREDICTION IN 2-YEAR-OLD CHILDREN WITH PREVIOUS CRITICAL CONDITION IN EARLY NEONATAL PERIOD | 2007 |
|
RU2336026C1 |
METHOD FOR EARLY PREDICTION OF CHORION AND PLACENTA DETACHMENT ON BASIS OF DETECTING GENE POLYMORPHISM OF TYPE 1 PLASMINOGEN ACTIVATOR INHIBITOR (PAI-1) | 2012 |
|
RU2494400C1 |
METHOD OF EARLY PREDICTION OF PREECLAMPSIA PROGRESSION | 2016 |
|
RU2648872C1 |
METHOD FOR ASSESSMENT OF CONTRIBUTION OF FETAL THROMBOPHILIA IN FORMATION OF SUB- AND DECOMPENSATED FORMS OF PLACENTAL INSUFFICIENCY | 2017 |
|
RU2677466C1 |
METHOD FOR PROGNOSIS OF SEVERITY OF DISSEMINATED BLOOD COAGULATION ACUTE SYNDROME USING INTRAVASCULAR GENETIC MONITORING | 2005 |
|
RU2303262C2 |
Authors
Dates
2024-05-06—Published
2023-03-09—Filed