FIELD: medicine.
SUBSTANCE: provided is a method for treating a tumor by means of combined therapy using lenvatinib and (6S,9aS)–N–benzyl–8–({6–[3–(4–ethylpiperazin–1–yl)azetidin–1–yl]pyridin–2–yl}methyl)–6–(2–fluoro–4–hydroxybenzyl)–4,7–dioxo–2–(prop–2–en–1–yl)hexahydro–2H–pyrazino[2,1–c][1,2,4]triazine-1(6H)-carboxamide.
EFFECT: improved procedure of treating a tumor.
12 cl, 22 dwg, 13 ex, 10 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| CRYSTAL (6S,9AS)-N-BENZYL-8-({6-[3-(4-ETHYLPIPERAZIN-1-YL)AZETIDIN-1-YL]PYRIDIN-2-YL}METHYL)-6-(2-FLUORINE-4-HYDROXYBENZYL)-4,7-DIOXO-2-(PROP-2-EN-1-YL)HEXAHYDRO-2H-PYRAZINO[2,1-C][1,2,4]TRIAZINE-1(6H)-CARBOXAMIDE | 2016 |
|
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