FIELD: immunology; medicine.
SUBSTANCE: invention is related in particular to a complex intended for use in the prevention and/or treatment of cancer, wherein the complex contains a) a cell-penetrating peptide, b) at least three antigenic epitopes and c) at least one peptide agonist TLR, in which components a)-c) are covalently linked. In particular, compositions are described for use in the prevention and/or treatment of colorectal cancer, such as pharmaceutical compositions and vaccines.
EFFECT: present invention makes it possible to obtain a new complex for use in immunotherapy of colorectal cancer, which is a more effective vaccine, primarily an anti-cancer vaccine, which has improved antitumor activity, intended for the prevention and/or treatment of colorectal cancer.
47 cl, 76 dwg, 46 ex
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