2,3-DIHYDRO-ISOINDOL-1-ONE DERIVATIVES AND METHODS FOR USE THEREOF AS BRUTON'S TYROSINE KINASE INHIBITORS Russian patent published in 2018 - IPC C07D403/04 A61K31/4178 A61P35/00 A61P25/00

Abstract RU 2671847 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention relates to a compound of formula (1), its pharmaceutically acceptable salts, and also to pharmaceutical compositions containing the compound as an active ingredient; and a method of treating, alleviating or preventing diseases using said compound. (I).

EFFECT: obtaining novel compounds that are useful for treating, alleviating or preventing diseases caused by abnormal or uncontrolled activation of protein kinase, such as BTK.

23 cl, 5 tbl, 20 ex

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RU 2 671 847 C2

Authors

Khon En Ne

Na Chon Yn

Min Im Suk

Chkha Khen Chu

Kvon Sul Ki

No Songu

Cho Chun Men

Dates

2018-11-07—Published

2013-12-26—Filed