FIELD: chemistry.
SUBSTANCE: invention relates to N-(4-(azaindazol-6-yl)-phenyl)-sulfonamides of the formula I in which Ar, n, X, Z, R1, R2 and R3 have the meanings indicated in the claims. Invention also relates to a process for the preparation of a compound, as well as to the composition and use of the compound as an inhibitor of the serum and glucocorticoid-regulated kinase
.
EFFECT: this compound has the ability to effectively inhibit the aberrant activity of SGK in a pathological context and has high bioavailability, stability in plasma and liver and selectively does not affect other kinases and receptors.
15 cl, 11 tbl, 699 ex
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