METHOD OF SELECTING PATIENTS AT RISK GROUP FOR DEVELOPMENT OF FOLLICULAR ANGINA Russian patent published in 2018 - IPC G01N33/52 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, in particular to microbiology and otolaryngology, and can be used to select patients to the risk group for the development of follicular angina associated with non-diphtheria corynebacteria. To do this, examine the patient's oropharyngeal discharge, in which the concentration of non-diphtheria corynebacteria (K), CFU/ml is determined. When the K value is ≥10⁴, additionally determine the characteristics of non-diphtheria corynebacteria: the value of the average adhesion index (AAI) to Hep-2 pharyngeal epithelial cells, the value of the average invasion index (AII) in the Hep-2 pharyngeal epithelial cells, the absence or presence of hemolytic activity of bacteria and the absence or presence of urease. Determine the coefficients of adhesion (K₁), invasion (K₂), hemolytic activity (K₃) and urease (K₄). Depending on the value of AAI, AII, the presence of hemolytic activity and/or urease, the values of K₁ K₂, K₃, K₄ are assigned a numeric value from 0 to 2. Then calculate the risk coefficient (RC) of the development of follicular angina. When the RC≥4, the patient is selected to the risk group for the development of follicular angina.

EFFECT: invention allows to select at risk group for the development of follicular angina associated with non-diphtheria corynebacteria.

1 cl, 5 ex