METHOD FOR STUDYING KIDNEY FUNCTION IN MULTISPIRAL COMPUTED TOMOGRAPHY Russian patent published in 2018 - IPC A61B6/03 A61K49/06 A61P43/00 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to urology, nephrology and radiation diagnosis, and can be used to study kidney function in multispiral computed tomography. Three-dimensional multispiral computed tomography with intravenous contrast is performed. Carry out the native, arterial, venous, excretory phase of the transport of contrast medium in the kidneys. Next, the zones of interest are determined in the kidneys, which, according to 3D modeling data, are allocated volumes of cortical and brain substance of each kidney into each of the phases. Measures in the volumes of the cortical and medulla of each kidney are the values of the density of the contrast medium in units of Hounsfield (HU). Subtract from the value of the density of the contrast medium content of cortical and cerebral matter in the arterial phase indices into the native phase. After that, their integrals are calculated and the plasma current values are obtained separately as a percentage for each kidney. Further, from the integral of the density of the content of the contrast medium into the venous phase, subtract it from the arterial phase. Divide this indicator by the integral of the density of the contrast medium in the cortex into the arterial phase and the time elapsed between the arterial and venous phases and determine the relative rate of glomerular filtration. Then, value of the density of the content of the contrast medium released into the excretory phase is determined, on both sides separately and after dividing each of the indicators by their sum, the values of the perfusion of contrast medium through the kidneys are obtained as a percentage. Value of the density of the contrast medium content in the excretory phase is divided by the value of the density of the contrast medium introduced into the organism at the 7^th minute and the total percentage of the excretory function of the kidneys is determined.

EFFECT: method provides increase in accuracy of the study of the separate function of the kidneys, the reduction of additional X-ray-reduction of radiation load on the patient due to numerical analysis of data obtained with multispiral computed tomography with intravenous contrast.

1 cl, 5 dwg, 2 ex