FIELD: pharmaceuticals.
SUBSTANCE: invention relates to N-substituted N'-(1-alkyltetrazole-5-yl)-
trinitroacetimidamides of the general formula . In the general formula, R1=CH3; CH2-CH=CH2; Ad; R2=H; COOR3; R3=Me; Pr; i-Pr; t-bu; CH2Ph; CH2CH2F; CH2CH2Ad; (CH2) 7CH3; CH2C≡CH; . Invention also relates to a method of producing said compounds.
EFFECT: technical result: new N-substituted N'-(1-alkyltetrazole-5-yl)-trinitroacetimidamides with cytotoxic activity are obtained.
2 cl, 3 ex, 3 tbl
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Authors
Dates
2019-01-16—Published
2016-12-22—Filed