N-SUBSTITUTED N'-(1-ALKYLTETRAZOLE-5-YL)-TRINITROACETIMIDAMIDES AND METHOD FOR PRODUCTION THEREOF Russian patent published in 2019 - IPC C07D257/04 C07D405/12 A61K31/395 

Abstract RU 2677337 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to N-substituted N'-(1-alkyltetrazole-5-yl)-

trinitroacetimidamides of the general formula . In the general formula, R1=CH3; CH2-CH=CH2; Ad; R2=H; COOR3; R3=Me; Pr; i-Pr; t-bu; CH2Ph; CH2CH2F; CH2CH2Ad; (CH2) 7CH3; CH2C≡CH; . Invention also relates to a method of producing said compounds.

EFFECT: technical result: new N-substituted N'-(1-alkyltetrazole-5-yl)-trinitroacetimidamides with cytotoxic activity are obtained.

2 cl, 3 ex, 3 tbl

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RU 2 677 337 C2

Authors

Bakharev Vladimir Valentinovich

Gidaspov Aleksandr Aleksandrovich

Zalomlenkov Vladimir Aleksandrovich

Parfenov Viktor Evgenevich

Dates

2019-01-16Published

2016-12-22Filed