N-(2-(2-(2-AZIDOETHOXY)ETHOXY)ETHYL)-4,6-DI(AZIRIDIN-1-YL)-1,3,5-TRIAZIN-2-AMINE, HAVING CYTOTOXIC ACTION Russian patent published in 2024 - IPC C07D403/14 A61K31/53 A61P35/00 

Abstract RU 2825828 C1

FIELD: chemistry.

SUBSTANCE: invention relates to a novel chemical compound, namely N-(2-(2-(2-azidoethoxy)ethoxy)ethyl)-4,6-di(aziridin-1-yl)-1,3,5-triazin-2-amine, which is 1,3,5-triazine derivative and has cytotoxic action.

EFFECT: novel compound having pronounced cytotoxic action, which can be used as an active ingredient in making anticancer drugs, is obtained.

1 cl, 2 tbl

Similar patents RU2825828C1

Title Year Author Number
METHYL 6-[(4-(AZIRIDIN-1-YL)-6-CHLORO-1,3,5-TRIAZIN-2-YL)AMINO]HEXANOATE, WHICH HAS A CYTOTOXIC EFFECT 2022
  • Molchanov Oleg Evgenevich
  • Semenov Konstantin Nikolaevich
  • Sharoiko Vladimir Vladimirovich
  • Popova Elena Aleksandrovna
  • Protas Aleksandra Vladimirovna
  • Mikolaichuk Olga Vladislavovna
  • Popova Alena Aleksandrovna
  • Maistrenko Dmitrii Nikolaevich
RU2791798C1
DERIVATIVES OF 2-R1-4-R2-6-POLYNITROMETHYL-1,3,5-TRIAZINES, POSSESSING ANTIBACTERIAL ACTIVITY 2013
  • Malyshev Boris Sotivoldievich
  • Evdokimov Aleksej Al'Bertovich
  • Netesova Nina Aleksandrovna
  • Malygin Ehrnst Georgievich
  • Bormotov Nikolaj Ivanovich
  • Shishkina Larisa Nikolaevna
  • Gidaspov Aleksandr Aleksandrovich
  • Bakharev Vladimir Valentinovich
  • Klimochkin Jurij Nikolaevich
RU2541525C2
5-OXYMETHYL-5-[3-(2-CHLORETHYL)-3- NITROZOUREIDO]-2-CYCLOHEXYL- 1 2000
  • Kon'Kov S.A.
  • Stukov A.N.
  • Ivin B.A.
  • Filov V.A.
RU2179555C1
USE OF CYTOTOXIC AGENTS BASED ON SUBSTITUTED POTASSIUM 1-AMINO-1,6-DIOXO-2-CYANO-1-ETHOXY-6-R1-4-[((3-ETHOXYCARBONYL)-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-yl)AMINO]HEXA-2,4-DIEN-3-OLATES IN TREATMENT OF LUNG MELANOMA 2023
  • Shipilovskikh Sergei Aleksandrovich
  • Timin Aleksandr Sergeevich
RU2808533C1
NEW STERICALLY HINDERED PHENOLS CONTAINING BENZOFUROXAN FRAGMENTS WITH ANTITUMOR ACTIVITY 2022
  • Chugunova Elena Aleksandrovna
  • Burilov Aleksandr Romanovich
  • Gibadullina Elmira Mingaleevna
  • Voloshina Aleksandra Dmitrievna
  • Liubina Anna Pavlovna
  • Amerkhanova Siumbelia Kamilevna
  • Nguen Khoang Bao Chan
  • Alabugin Igor Vladimirovich
  • Matylitskii Kirill Vladimirovich
RU2796810C1
2-(1,1-DIMETHYL-1H-BENZO[E]INDOLIN-2-YL)-5,6,7-TRICHLORO-1,3-TROPOLONE, WHICH HAS CYTOTOXIC ACTIVITY AGAINST A431 SKIN CANCER AND H1299 LUNG CANCER CELL CULTURES 2023
  • Minkin Vladimir Isaakovich
  • Kit Oleg Ivanovich
  • Saiapin Iurii Anatolevich
  • Maksimov Aleksei Iurevich
  • Goncharova Anna Sergeevna
  • Gusakov Evgenii Aleksandrovich
  • Tupaeva Inna Olegovna
  • Krasnikova Tatiana Anatolevna
  • Kuznetsova Natalia Sergeevna
  • Filippova Svetlana Iurevna
  • Chembarova Tatiana Vladimirovna
RU2810581C1
AGENT HAVING CYTOTOXIC ACTIVITY ON NON-SMALL-CELL LUNG CANCER CELL CULTURE A 549 2020
  • Minkin Vladimir Isaakovich
  • Kit Oleg Ivanovich
  • Goncharova Anna Sergeevna
  • Lukbanova Ekaterina Alekseevna
  • Saiapin Iurii Anatolevich
  • Gusakov Evgenii Aleksandrovich
  • Turkin Igor Nikolaevich
  • Sitkovskaia Anastasiia Olegovna
  • Fillipova Svetlana Iurevna
  • Leiman Igor Aleksandrovich
  • Lazutin Iurii Nikolaevich
  • Chubarian Anna Vasilevna
  • Pashchenko Denis Georgievich
  • Tishchenko Irina Sergeevna
RU2741311C1
(E)-5-AMINO-2-OXO-1-(2-(NAPHTHALEN-2-YL)-2-OXOETHYLIDENE)-1,2,6,7,8,9-HEXAHYDROBENZO[4,5]THIENO[3,2-E]PYRROLO[1,2-A]PYRIMIDINE-3-CARBOXAMIDE, HAVING ANTICANCER ACTIVITY IN BREAST CANCER THERAPY 2023
  • Karpov Timofei Evgenevich
  • Rogova Anna
  • Timin Aleksandr Sergeevich
  • Shipilovskikh Sergei Aleksandrovich
RU2820661C1
MIXED-LIGAND COMPLEXES OF COPPER (II) WITH 1H-TETRAZOLE-5-ACETIC ACID AND OLIGOPYRIDINE DERIVATIVES, EXHIBITING CYTOTOXIC ACTIVITY 2023
  • Lider Elizaveta Viktorovna
  • Ermakova Ekaterina Andreevna
  • Golubeva Yuliya Andreevna
  • Klyushova Lyubov Sergeevna
  • Smirnova Kseniya Sergeevna
RU2818953C1
RECOMBINANT EL1 PEPTIDE HAVING CYTOTOXIC ACTIVITY RELATIVE TO HUMAN CANCER CELLS 2017
  • Koval Olga Aleksandrovna
  • Volkova Olga Yurevna
  • Gorchakov Andrej Aleksandrovich
  • Kulemzin Sergej Viktorovich
  • Tkachenko Anastasiya Viktorovna
  • Nushtaeva Anna Andreevna
  • Kuligina Elena Vladimirovna
  • Rikhter Vladimir Aleksandrovich
  • Taranin Aleksandr Vladimirovich
RU2683221C1

RU 2 825 828 C1

Authors

Molchanov Oleg Evgenevich

Popova Elena Aleksandrovna

Maistrenko Dmitrii Nikolaevi

Semenov Konstantin Nikolaevich

Protas Aleksandra Vladimirovna

Mikolaichuk Olga Vladislavovna

Popova Alena Aleksandrovna

Sharoiko Vladimir Vladimirovich

Shemchuk Olga Sergeevna

Golub Valeriia Mikhailovna

Dates

2024-08-30Published

2023-12-29Filed