FIELD: medicine.
SUBSTANCE: invention is intended to diagnose the severity of chronic generalized periodontitis (CGP) in pregnant women. In the second trimester of a pregnant woman, oral and gingival fluids are collected. In the oral fluid determine the content of osteoprotegrin (OPG), pg/ml. In the gingival fluid determine the concentration of Cathelicidin LL37 (C), pg/ml. With simultaneous fulfillment of conditions 99.7≥OPG>93.3 and 16.0≤C<19.1 mild CGP is diagnosed. With simultaneous fulfillment of conditions 93.3≥OPG>82.1 and 19.1≤C<23.3 moderate CGP is diagnosed. With simultaneous fulfillment of the conditions of the OPG≤82.1 and C≥23.3 severe CGD is diagnosed.
EFFECT: proposed invention allows non-invasive and with high reliability to diagnose the severity of CGP in pregnant women.
1 cl, 3 ex
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