FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, specifically to the use of peptide inhibitors of ActRIIB, and can be used in medicine for the treatment of atherosclerotic calcification.
EFFECT: invention allows to reduce or alleviate one or more symptoms of vascular calcification in an individual, such as an increase in vascular calcium levels, increased apoptosis of vascular smooth muscle cells, loss of elasticity of the arteries, an increase in the speed of the pulse wave, the development of left ventricular hypertrophy, a decrease in perfusion of the coronary arteries and myocardial ischemia.
14 cl, 11 dwg, 6 tbl, 1 ex
