Show metadata Hide metadata

(19)

(11)

2 678 768

(13)

(51)

IPC

A61K38/16(2006-01-01)

A61K38/18(2006-01-01)

C07K14/505(2006-01-01)

A61P13/00(2006-01-01)

(21) (22)

Application

2018133675, 2018-09-25

(24)

Start date

2018-09-25

(22)

Actual filing date

2018-09-25

(45)

Published

2019-02-01

(72)

Inventor

Kostina Darya AleksandrovnaPokrovskaya Tatyana GrigorevnaPokrovskij Mikhail VladimirovichGureev Vladimir VladimirovichYakushev Vladimir IvanovichPeresypkina Anna AleksandrovnaKolesnichenko Pavel Dmitrievich

(73)

Holder

Federalnoe Gosudarstvennoe Avtonomnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennyj Natsionalnyj Issledovatelskij Universitet"

METHOD FOR PREVENTING RENAL ISCHEMIA REPERFUSION INJURY BY CARBAMYLATED DARBEPOETIN IN EXPERIMENT Russian patent published in 2019 - IPC A61K38/16 A61K38/18 C07K14/505 A61P13/00

Abstract RU 2678768 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine and is intended for the prevention of renal ischemia reperfusion injury in the experiment. When simulating renal ischemia reperfusion injury, male Wistar rats by imposing atraumatic clamps on the renal pedicle are injected with carbamylated darbepoetin at a dose of 50 mcg/kg subcutaneously in the top of shoulder 24 hours before ischemia induction for 40 minutes. Evaluation of nephroprotective properties carried out after 24 and 72 hours.

EFFECT: method provides an increase in the effectiveness of the prevention of ischemia reperfusion disorders of the kidneys.

1 cl, 1 ex, 2 tbl

Similar patents RU2678768C1

Title	Year	Author	Number
METHOD FOR PREVENTING ISCHEMIA-REPERFUSION RENAL INJURIES WITH AN INHIBITOR OF ARGINASE II IN EXPERIMENT	2018	Elagin Vladislav Viktorovich Bratchikov Oleg Ivanovich Pokrovskij Mikhail Vladimirovich Pokrovskaya Tatyana Grigorevna Kostina Darya Aleksandrovna Gureev Vladimir Vladimirovich Korokin Mikhail Viktorovich Korokina Liliya Viktorovna	RU2695333C1
METHOD FOR PREVENTING RENAL DYSFUNCTIONS WITH CARBAMYLATED DARBEPOETIN IN EXPERIMENT	2018	Kostina Darya Aleksandrovna Pokrovskaya Tatyana Grigorevna Pokrovskij Mikhail Vladimirovich Gureev Vladimir Vladimirovich Yakushev Vladimir Ivanovich Peresypkina Anna Aleksandrovna Kolesnichenko Pavel Dmitrievich	RU2695334C1
METHOD FOR PREVENTING RENAL DYSFUNCTION WITH AN ARGINASE II INHIBITOR IN EXPERIMENT	2018	Elagin Vladislav Viktorovich Bratchikov Oleg Ivanovicha Pokrovskij Mikhail Vladimirovich Pokrovskaya Tatyana Grigorevna Kostina Darya Aleksandrovna Gureev Vladimir Vladimirovich Korokin Mikhail Viktorovich Korokina Liliya Viktorovna	RU2696580C1
METHOD FOR PREVENTING MICROCIRCULATION DISORDERS IN KIDNEYS WITH ASIALISED ERYTHROPOIETIN IN EXPERIMENT	2018	Elagin Vladislav Viktorovich Bratchikov Oleg Ivanovich Pokrovskij Mikhail Vladimirovich Pokrovskaya Tatyana Grigorevna Kostina Darya Aleksandrovna Gureev Vladimir Vladimirovich Pobeda Anna Sergeevna Shchurovskaya Kristina Vladimirovna	RU2696864C1
METHOD FOR CORRECTING MICROCIRCULATION DISORDERS IN KIDNEY WITH INFLIXIMAB IN ISCHEMIA-REPERFUSION INJURY	2021	Netrebenko Aleksandr Sergeevich Gureev Vladimir Vladimirovich Korokin Mikhail Viktorovich Pokrovskij Mikhail Vladimirovich Soldatov Vladislav Olegovich Pokrovskaya Tatyana Grigorevna Peresypkina Anna Aleksandrovna Gudyrev Oleg Sergeevich Shkodkin Sergej Valentinovich Zatolokina Mariya Alekseevna Pobeda Anna Sergeevna Pokrovskij Vladimir Mikhajlovich Korokina Liliya Viktorovna Gureeva Anastasiya Vladimirovna Kochkarova Indira Sultanovna Kolesnik Inga Mikhajlovna Burda Yurij Evgenevich Alekhin Sergej Aleksandrovich Kostina Darya Aleksandrovna Poltev Vladimir Yurevich	RU2753247C1
METHOD FOR CORRECTING MICROCIRCULATION DISORDERS IN KIDNEY WITH PEPTIDE THAT MIMICS ALPHA-HELIX B OF ERYTHROPOIETIN IN ISCHEMIA-REPERFUSION INJURY	2021	Netrebenko Aleksandr Sergeevich Gureev Vladimir Vladimirovich Korokin Mikhail Viktorovich Pokrovskij Mikhail Vladimirovich Soldatov Vladislav Olegovich Pokrovskaya Tatyana Grigorevna Peresypkina Anna Aleksandrovna Gudyrev Oleg Sergeevich Shkodkin Sergej Valentinovich Zatolokina Mariya Alekseevna Pobeda Anna Sergeevna Pokrovskij Vladimir Mikhajlovich Korokina Liliya Viktorovna Gureeva Anastasiya Vladimirovna Kochkarova Indira Sultanovna Kolesnik Inga Mikhajlovna Burda Yurij Evgenevich Alekhin Sergej Aleksandrovich Kostina Darya Aleksandrovna Poltev Vladimir Yurevich	RU2751413C1
METHOD OF AGENT APPLICATION BASED ON HUMAN MODIFIED PEROXYREDOXIN 2 FOR CORRECTING CONSEQUENCES OF ISCHEMIC-REPERFUSIVE KIDNEY DAMAGE	2020	Goncharov Ruslan Georgievich Novoselov Vladimir Ivanovich Sharapov Mars Galievich	RU2747121C1
AGENT FOR CORRECTION OF ACUTE RENAL INSUFFICIENCY IN TOXIC HEPATORENAL SYNDROME INDUCED BY CARBON TETRACHLORIDE AND METHOD FOR CORRECTION OF ACUTE RENAL INSUFFICIENCY IN TOXIC HEPATORENAL SYNDROME INDUCED BY CARBON TETRACHLORIDE	2004	Shilenok Ivan Grigor'Evich Panina Natal'Ja Aleksandrovna Mukhina Irina Vasil'Evna	RU2290940C2
LITHIUM SALTS ADMINISTRATION FOR TREATING ACUTE RENAL INSUFFICIENCY	2008	Zorov Dmitrij Borisovich Sukhikh Gennadij Tikhonovich Plotnikov Egor Jur'Evich Vasil'Eva Alena Konstantinovna Kirpatovskij Vladimir Igorevich Kazachenko Aleksandr Viktorovich Khrjapenkova Tat'Jana Gennad'Evna Isaev Nikolaj Konstantinovich Zorova Ljubava Dmitrievna Pevzner Irina Borisovna Marej Marija Vladimirovna	RU2409373C2
DIAGNOSTIC TECHNIQUE FOR REPERFUSION SYNDROME	2010	Timerbulatov Vil' Mamilovich Fajazov Radik Radifovich Mekhdiev Dzhamaladdin Isa-Ogly Timerbulatov Shamil' Vilevich Sultanbaev Artur Uralovich Gareev Rustam Nazirovich Akhmerov Ruslan Rimovich Sakhautdinov Rais Maratovich	RU2424526C1

RU 2 678 768 C1

Authors

Kostina Darya Aleksandrovna

Pokrovskaya Tatyana Grigorevna

Pokrovskij Mikhail Vladimirovich

Gureev Vladimir Vladimirovich

Yakushev Vladimir Ivanovich

Peresypkina Anna Aleksandrovna

Kolesnichenko Pavel Dmitrievich

Dates

2019-02-01—Published

2018-09-25—Filed