METHOD FOR PREVENTING MICROCIRCULATION DISORDERS IN KIDNEYS WITH ASIALISED ERYTHROPOIETIN IN EXPERIMENT Russian patent published in 2019 - IPC A61K38/16 A61K38/18 A61P13/12 

Abstract RU 2696864 C1

FIELD: medicine.

SUBSTANCE: present invention refers to medicine, namely to experimental pharmacology and urology, and concerns preventing ischemia-reperfusion renal injury experimentally. That is ensured by administering asialised erythropoietin to male rats of Wistar line. Renal pathology is then simulated by applying atraumatic clamps on renal peduncles with subsequent reperfusion of blood flow in 40 minutes. Asialised erythropoietin is administered in dose of 2.4 mcg/kg intraperitoneal by 30 minutes before simulating the pathology.

EFFECT: method provides effective prevention of renal ischemic injuries by improving microcirculation processes.

1 cl, 1 ex, 1 tbl

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RU 2 696 864 C1

Authors

Elagin Vladislav Viktorovich

Bratchikov Oleg Ivanovich

Pokrovskij Mikhail Vladimirovich

Pokrovskaya Tatyana Grigorevna

Kostina Darya Aleksandrovna

Gureev Vladimir Vladimirovich

Pobeda Anna Sergeevna

Shchurovskaya Kristina Vladimirovna

Dates

2019-08-07Published

2018-09-24Filed