FIELD: medicine.
SUBSTANCE: invention relates to medicine, in particular to experimental pharmacology and urology, and can be used to correct disorders of microcirculation in the kidney. The method for correcting microcirculation disorders in the kidney includes reproducing a model of ischemia-reperfusion kidney injuries by applying atraumatic vascular clamps on the left renal pedicle for 40 minutes. To correct microcirculation, infliximab is administered intraperitoneally at a dosage of 10 mg/kg once 1 hour before ischemia.
EFFECT: invention provides creation of an effective method for correcting microcirculation in the kidney when modeling ischemia-reperfusion kidney damage.
1 cl, 1 tbl, 1 ex
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RU2735766C1 |
