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2 695 334

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IPC

A61K38/16(2006-01-01)

A61K38/18(2006-01-01)

A61P13/12(2006-01-01)

(21) (22)

Application

2018133815, 2018-09-25

(24)

Start date

2018-09-25

(22)

Actual filing date

2018-09-25

(45)

Published

2019-07-23

(72)

Inventor

Kostina Darya AleksandrovnaPokrovskaya Tatyana GrigorevnaPokrovskij Mikhail VladimirovichGureev Vladimir VladimirovichYakushev Vladimir IvanovichPeresypkina Anna AleksandrovnaKolesnichenko Pavel Dmitrievich

(73)

Holder

Federalnoe Gosudarstvennoe Avtonomnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennyj Natsionalnyj Issledovatelskij Universitet"

METHOD FOR PREVENTING RENAL DYSFUNCTIONS WITH CARBAMYLATED DARBEPOETIN IN EXPERIMENT Russian patent published in 2019 - IPC A61K38/16 A61K38/18 A61P13/12

Abstract RU 2695334 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to experimental pharmacology and urology, and concerns prevention of renal dysfunction in experiment. That is ensured by introducing carbamylated darbepoetin in dose of 50 mcg/kg subcutaneously into a wit area in white labs 24 hours prior to modeling the renal pathology by applying non-traumatic clamps onto the renal pedicles for 40 minutes, followed by reperfusion of blood flow in the kidneys.

EFFECT: administering the preparation at an experimentally set time in the declared dose provides effective prevention of renal ischemia reperfusion disorders.

1 cl, 1 ex, 2 tbl

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RU 2 695 334 C1

Authors

Kostina Darya Aleksandrovna

Pokrovskaya Tatyana Grigorevna

Pokrovskij Mikhail Vladimirovich

Gureev Vladimir Vladimirovich

Yakushev Vladimir Ivanovich

Peresypkina Anna Aleksandrovna

Kolesnichenko Pavel Dmitrievich

Dates

2019-07-23—Published

2018-09-25—Filed