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2 679 622

(13)

(51)

IPC

C07D413/14(2006-01-01)

A61K31/535(2006-01-01)

A61P37/00(2006-01-01)

(21) (22)

Application

2016118619, 2014-10-14

(24)

Start date

2014-10-14

(22)

Actual filing date

2014-10-14

(45)

Published

2019-02-12

(72)

Inventor

Karlson ErikKhansen KhansMakki MettyuShiller ShonOgava TikakoDevis KhiterEndo AtsusiKhokins LinnIsizaka Salli

(73)

Holder

Ejsaj Ar End Di Menedzhment Ko., Ltd.

SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS Russian patent published in 2019 - IPC C07D413/14 A61K31/535 A61P37/00

Abstract RU 2679622 C2

FIELD: medicine.

SUBSTANCE: invention relates to quinolone compounds of formulae (I), (II), (III) and use thereof in pharmaceutical compositions effective for treating systemic lupus erythematosus (SLE) and lupus nephritis.

EFFECT: novel compounds which act as antagonists or inhibitors of Toll-like receptors (TLR) 7 are obtained.

39 cl, 9 tbl, 9 dwg

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RU 2 679 622 C2

Authors

Karlson Erik

Khansen Khans

Makki Mettyu

Shiller Shon

Ogava Tikako

Devis Khiter

Endo Atsusi

Khokins Linn

Isizaka Salli

Dates

2019-02-12—Published

2014-10-14—Filed