COMPOUNDS USEFUL FOR TREATING DISEASES CAUSED BY RETROVIRUSES Russian patent published in 2019 - IPC A61K31/33 A61K31/444 A61P31/12 

Abstract RU 2681943 C9

FIELD: medicine.

SUBSTANCE: invention relates to medicine and can be used to use a compound of formula (Iq) for the preparation of a medicament for the treatment of a retroviral infection and a pharmaceutically acceptable salt thereof, where the retroviral infection is caused by a retrovirus, which is the human leukemia virus HTLV1. Compound is represented by formula (Iq) (Iq), where R independently represents a hydrogen atom, (C1-C3)alkoxy group or (C1-C3)fluoroalkoxy group, R'' represents a hydrogen atom, R' represents a hydrogen atom or a group selected from the group -NR1R2, N-methylpiperazinyl group, (C1-C3)alkoxy and morpholino groups, R1 and R2 independently represent a hydrogen atom or (C1-C3)alkyl group, n equals 1, n' equals 1.

EFFECT: use of this compound can inhibit the splicing of the retrovirus RNA, effectively inhibiting HTLV1.

1 cl, 2 tbl, 10 ex

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RU 2 681 943 C9

Authors

Tazi Zhamal

Mayuto-Betzer Florens

Nazhman Romen

Sherrer Dide

Kampo Noeli

Garsel Od

Dates

2019-03-14Published

2014-07-04Filed