COMPOUNDS APPLICABLE FOR TREATING AIDS Russian patent published in 2016 - IPC C07D401/12 C07D403/12 C07D215/04 C07D215/18 C07D215/24 C07D241/42 A61K31/4427 A61K31/4709 A61K31/497 A61K31/498 A61K31/506 A61P31/18 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to using a compound of formula

or any of its pharmaceutically acceptable salts, wherein means an aromatic ring, wherein V represents C or N, and when V represents N, V is found in meta- or para-position to Z, R independently represents a hydrogen atom, halogen atom or group specified in -CN group, hydroxyl group, -COOR₁ group, (C₁-C₃)fluoralkyl group, (C₁-C₃)fluoralkoxy group, -NO₂ group, -NR₁R₂ group, (C₁-C₄)alkoxy group, phenoxy group and (C₁-C₃)alkyl group, wherein the above alkyl is optionally monosubstituted by a hydroxyl group, R₁ and R₂ independently represent a hydrogen atom or (C₁-C₃)alkyl group, n is equal to 1, 2 or 3, n′ is equal to 1 or 2, R′ represents a hydrogen atom, halogen atom or group specified in (C₁-C₃)alkyl group, -NO₂ group, -NR₁R₂ group, morpholinyl group, N-methylpiperazinyl group, (C₁-C₃)fluoralkyl group and (C₁-C₄)alkoxy group, R″ represents a hydrogen atom, Z, Y, X, W, T and U represent N or C, and wherein at most four of V, T, U, Z, Y, X and W groups represent N, and at least one of T, U, Y, X and W groups represents N, for producing a medicinal preparation for preventing, inhibiting or treating AIDS. The invention also refers to using specific compounds, new quinoline derivatives, a pharmaceutical composition based on the new quinoline derivatives.

EFFECT: new quinoline derivatives are produced, and new biological activity of known compounds is stated.

15 cl, 2 tbl, 11 ex