FIELD: medicine.
SUBSTANCE: invention relates to use of compound (S)-bicalutamide and/or structural analogue, which are collectively determined by general formula (II), as well as their pharmaceutically acceptable salts, hydrates and/or solvates for preventing clinical symptoms and/or treatment of diseases and/or disorders of lysosomal accumulation and/or glycogenosis. In formula (II) R1 is halogen (F, Cl, Br or I), R4 is a trifluoromethyl group (-CF3), R5 is a nitrile (-CN) group, X is a thioether (S), a sulphoxide (SO), a sulphone (SO2) or oxygen (O). (II).
EFFECT: invention also relates to use of said compounds in diagnosing diseases and/or disorders of lysosomal accumulation and/or glycogenosis and using a pharmaceutical composition containing said compounds.
11 cl, 1 dwg, 5 tbl, 6 ex
Authors
Dates
2019-04-17—Published
2014-12-19—Filed