METHODS AND TREATMENT OF CERTAIN DISORDERS BASED ON DEMYELINATION AND DEMYELINATION AND/OR REMYELINATION STIMULATION Russian patent published in 2019 - IPC A61K33/24 A61K9/14 B82Y5/00 

FIELD: medicine.

SUBSTANCE: group of inventions relates to neurology and concerns using a therapeutically effective amount of a composition for preparing a medicament for stimulating remyelination of neurons in a mammal, wherein said neurons are demyelinated by cell respiration disorders. Composition contains a.) water of pharmaceutical category; b.) at least one processing amplifier selected from a group of materials consisting of sodium bicarbonate, sodium carbonate, potassium bicarbonate, potassium carbonate, sodium triphosphate, sodium diphosphate, sodium monophosphate and potassium phosphates; and c.) gold nanocrystals, suspended in said water to form a suspension. Said nanocrystals: i.) have surfaces which include at least one characteristic selected from a group of characteristics consisting of: (1) organic chemical components are not attached to or do not stick to said surfaces, and/or (2) they have a clean surface and have no chemical components attached or adhered to surfaces other than water or said processing amplifier, which change operation of said nanocrystals; ii.) have a particle size modulus of less than 50 nm; iii.) are present in said suspension in concentration of 2–3000 ppm; and d.) said suspension has pH of 5 to 9.5 and a zeta potential of at least -30 mV. Also presented is using a therapeutically effective amount of the nanosuspension for preparing a medicinal agent for treating a disease in a mammal, including neuron demyelination caused by cellular respiration disorder in said neurons, wherein said drug stimulates remyelination of said neurons.

EFFECT: group of inventions provides stimulating neuronal remyelination in a mammal, wherein said neurons are demyelinated by cell respiration disorder, wherein the composition contains elementary gold nanosuspension.

12 cl, 51 dwg, 5 tbl, 3 ex