OLIGONUCLEOTIDE SEQUENCE OLIGONUCLEOTIDE SEQUENCE FOR THE NRAS GENE Q61R MUTATION IN THE TUMOR FORMATIONS OF THE THYROID GLAND Russian patent published in 2019 - IPC G01N33/58 C12Q1/6827 

Abstract RU 2688189 C1

FIELD: medicine.

SUBSTANCE: proposed group of inventions relates to medicine. Disclosed are a method and a kit for detecting Q61R mutation in a NRAS protein in a human tumor tissue sample. Method involves obtaining a sample of biological material taken from a patient, recovering DNA from said sample and carrying out PCR using a kit for detecting Q61R mutation in a NRAS protein.

EFFECT: presented group of inventions enables higher specificity and sensitivity of determining the presence of a mutant allele at the Q61R point of the NRAS gene, as well as reducing the probability of process errors during laboratory manipulations.

3 cl, 1 dwg, 1 tbl, 1 ex

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RU 2 688 189 C1

Authors

Kochergina-Nikitskaya Irina Nikolaevna

Vladimirova Ulyana Sergeevna

Rumyantsev Pavel Olegovich

Dates

2019-05-21Published

2019-02-20Filed