LACTOFERRIN FOR TREATING IBD CAUSED BY BACTERIAL INVASION Russian patent published in 2019 - IPC A61K38/40 A61K9/22 A61P1/04 A61P31/04

Abstract RU 2689987 C2

FIELD: medicine.

SUBSTANCE: invention refers to pharmacy and medicine. Disclosed is a delayed and / or delayed release oral composition for treating inflammatory intestinal diseases caused by invasion of invasive Escherichia coli (AIEC), including lactoferrin immersed in the core of a reservoir coated with a semipermeable film, or dissolved, and / or dispersed, and / or included in a matrix containing lipids, hydrophilic, amphiphilic substances and mixtures thereof, and the outer coating contains gastric-resistant coating agents (shellac, polymethacrylates, cellulose derivatives) or the semi-permeable film comprises cellulose derivatives.

EFFECT: technical result consists in reducing adhesion of AIEC to intestinal cells Caco-2 and reducing their invasion in said cells.

7 cl, 5 dwg, 9 ex

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RU 2 689 987 C2

Authors

Terrutstsi Karlo

Terrutstsi Fabio

Dates

2019-05-30—Published

2014-09-04—Filed