LIQUID OPHTHALMOLOGICAL PRODUCT WITH SUPPRESSION OF REDUCTION OF DIBUTYLHYDROXYTOLUENE CONTENT Russian patent published in 2023 - IPC A61K9/08 A61K47/10 A61K47/14 A61K47/26 A61K47/36 A61K47/44 A61P27/02 

Abstract RU 2810709 C2

FIELD: ophthalmological products.

SUBSTANCE: following is disclosed: an ophthalmic liquid product contained in a container in which the inner wall surface consists of a resin including polybutylene terephthalate, and the ophthalmic liquid product contains: (A) 0.0005 to 0.005 w/v% dibutylated hydroxytoluene, (B) 0.05 to 0.3 w/v% xanthan gum thickener, (C) 0.01 to 0.1 w/v% one or more nonionic surfactants selected from the group consisting of polysorbate 80, polyoxyethylene hydrogenated castor oil 60 and polyethylene glycol monostearate, and having a pH of 6 to 8. A method of inhibiting the reduction of dibutylated hydroxytoluene is also disclosed.

EFFECT: group of inventions provides an increase in the stabilizing effect of a product containing dibutylhydroxytoluene.

3 cl, 14 tbl, 9 ex

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RU 2 810 709 C2

Authors

Matsuhisa, Keiichi

Dates

2023-12-28Published

2019-05-31Filed