CYTOMETRIC METHOD FOR PREDICTION OF CLINICAL OUTCOME OF WIDESPREAD PURULENT PERITONITIS Russian patent published in 2019 - IPC G01N33/48 

Abstract RU 2691742 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine and is a cytometric method for prediction of the outcome of widespread purulent peritonitis, including sampling and blood examination, characterized by the fact that the patients immediately after the diagnosis of WPP by flow cytometry are used to determine the percentage of B1-lymphocytes and activated T-regulatory cells in blood, after which T-cell regulation coefficient (TCRC) is calculated, which is a ratio of B1-lymphocytes percentage to percentage content of activated T-regulatory cells, and if the TCRC value is 4.23 or more, the unfavorable outcome of the WPP is predicted, while the TCRC value lower than 4.23 enables predicting the favorable outcome of the WPP.

EFFECT: method enables early detection of the risk of the unfavorable outcome and provides a high level of prediction reliability.

1 cl, 4 ex

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RU 2 691 742 C1

Authors

Savchenko Andrej Anatolevich

Kasparov Eduard Vilyamovich

Borisov Aleksandr Gennadevich

Cherdantsev Dmitrij Vladimirovich

Pervova Olga Vladimirovna

Kudryavtsev Igor Vladimirovich

Belenyuk Vasilij Dmitrievich

Dates

2019-06-18Published

2018-05-23Filed