METHOD FOR PREDICTION OF SEVERITY OF ISCHEMIC PROCESS OF HEART, CEREBRUM AND LOWER LIMBS BASED ON ASSESSMENT OF CENTRAL AND REGIONAL HAEMODYNAMICS OF ORGANS Russian patent published in 2019 - IPC A61B5/02 G06F17/00 G01N33/48 

FIELD: medicine.

SUBSTANCE: invention relates to prediction of severity of ischemic process of heart, brain and lower limbs based on assessment of central and regional haemodynamics of organs. What is presented is a method which involves measuring systolic blood pressure at a given time (SBP), heart rate (HR), a difference in systolic and arterial pressure and three days ago (ΔAP), activated partial thromboplastin time (APTT) and concentration of Ca²⁺ in blood [Ca²⁺]. Self-regulation criterion of central hemodynamic system Z is determined by formula

,

wherein parameter Z is used as a basic variable, on which membership functions are determined μ_r(Z), determining confidence in classification of severity of ischemic process of central hemodynamic system, wherein four classes are distinguished, characterizing severity r: r = n - norm; r = l is a latent state; r = p is a reversible state; r = c is a critical condition, the patient refers to that class of severity of ischemic process of central hemodynamic system, function of belonging of which is maximum, by value Z is determined function of severity of ischemic process of central hemodynamic system f_z(Z), integral levels of severity of ischemic process in heart U_h, brain U_b and lower extremities U_e, by which, taking into account the state of central hemodynamic system, severity of ischemic process for heart ST_h, for brain ST_b and lower extremities ST_e are determined by expressions: ST_h = f_Z(Z) + U_h∙[1-f_Z(Z)], ST_b = f_Z(Z) + U_b∙[1-f_Z(Z)], ST_e = f_Z(Z) + U_e∙[1-f_Z(Z)], on scales ST_h, ST_b and ST_e functions of belonging to the same gravity classes are determined, as for central hemodynamic system - for heart μ_r(ST_h), for cerebrum μ_r(ST_b), for lower extremities μ_r(ST_e), r = n, l, p, c, and for each organ severity is determined by maximum value of corresponding membership functions.

EFFECT: invention provides higher quality of prediction of degree of severity of central hemodynamic system, ischemic process of heart, cerebrum and lower extremities.

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