FUSED PROTEINS CONTAINING PDGF AND VEGF BINDING PARTS, AND METHODS FOR USE THEREOF Russian patent published in 2019 - IPC C07K14/71 C07K19/00 C12N15/62 C12N15/86 C12N5/73 C12N5/10 C12N7/01 C12P21/02 A61K38/18 A61P27/02 

Abstract RU 2692652 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology, specifically to production of PDGF and VEGF binding proteins and recombinant viral particles encoding fused proteins, and can be used in medicine. PDGF and VEGF-bound fused proteins are used in compositions for effective inhibition of PDGF-path and VEGF-path.

EFFECT: viral particles coding PDGF and VEGF binding fusion proteins are used in an effective therapy of corneal neovascularisation.

14 cl, 8 dwg, 5 ex

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RU 2 692 652 C2

Authors

Pechan Piter

Ardinger Dzheffri

Rubin Khillard

Uodsvort Semyuel

Skaria Abrakham

Dates

2019-06-25Published

2014-03-13Filed