FIELD: medicine.
SUBSTANCE: group of inventions relates to medicine, namely to vaccine prevention, and discloses a method for preparing a glycoconjugate comprising bacterial capsular polysaccharide conjugated to a carrier protein via (2-((2-oxoethyl)thio)ethyl)carbamate (eTEC) spacer, glycoconjugate, and the immunogenic composition containing said glycoconjugate.
EFFECT: inventions allow to obtain suitably blocked conjugates based on a carrier protein, which maintain the functional properties of the carrier and the conjugate itself retains the ability to induce the desired immune response.
16 cl, 15 tbl, 9 ex, 8 dwg
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