METHODS OF GLYCOCONJUGATION AND COMPOSITION Russian patent published in 2020 - IPC A61K39/385 A61K47/50 C07K14/31 A61P37/00 A61P31/00 

Abstract RU 2724840 C2

FIELD: medicine; biochemistry.

SUBSTANCE: group of inventions discloses glycoconjugates connected through eTEC containing a saccharide covalently conjugated with a carrier protein via (2-((2-oxoethyl)thio)ethyl)carbamate (eTEC) spacer, and immunogenic compositions containing such glycoconjugates.

EFFECT: group of inventions enables to obtain appropriately blocked carrier protein-based conjugates, which maintain the functional properties of the carrier and the conjugate itself retains the ability to induce the desired immune response.

13 cl, 8 dwg, 15 tbl, 9 ex

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RU 2 724 840 C2

Authors

Gu Jianxin

Kim Jin-Hwan

Prasad A. Krishna

Yang Yu-Ying

Dates

2020-06-25Published

2013-08-12Filed