FIELD: medicine; biochemistry.
SUBSTANCE: group of inventions discloses glycoconjugates connected through eTEC containing a saccharide covalently conjugated with a carrier protein via (2-((2-oxoethyl)thio)ethyl)carbamate (eTEC) spacer, and immunogenic compositions containing such glycoconjugates.
EFFECT: group of inventions enables to obtain appropriately blocked carrier protein-based conjugates, which maintain the functional properties of the carrier and the conjugate itself retains the ability to induce the desired immune response.
13 cl, 8 dwg, 15 tbl, 9 ex
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Authors
Dates
2020-06-25—Published
2013-08-12—Filed