FIELD: biochemistry.
SUBSTANCE: invention relates to a monoclonal antibody selectively binding human interferon beta-1a. Also disclosed are isolated DNA fragments encoding VH or VL coding said antibody, and an antigen-binding fragment of said antibody.
EFFECT: invention provides effective treatment of diseases associated with human interferon beta-1a.
4 cl, 3 tbl, 3 ex, 3 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| MONOCLONAL ANTIBODY CAPABLE OF NEUTRALIZING BIOLOGICAL ACTIVITY OF HUMAN INTERFERON BETA 1A | 2018 |
|
RU2729391C2 |
| HUMANISED NEUTRALIZING ANTIBODY TO HUMAN INTERFERON-BETA | 2019 |
|
RU2737466C1 |
| VARIABLE DOMAINS OF LIGHT AND HEAVY CHAIN OF THE MOUSE MONOCLONAL ANTIBODY AGAINST INTERFERON ALPHA (IFN-α) HUMAN ANTIGEN BINDING FRAGMENTS (FAb) AGAINST HUMAN IFN-α COMPRISING SAID DOMAINS | 2018 |
|
RU2694672C1 |
| RECOMBINANT Fab-scFv BASED ON A NEUTRALISING ANTIBODY AGAINST HUMAN BETA-1A INTERFERON AND AN ANTIBODY AGAINST HUMAN ErbB2 RECEPTOR | 2019 |
|
RU2748953C1 |
| MONOCLONAL ANTIBODY, LINKING WITH E-BIR VIRUS GLOBE-PROTEIN, DNA FRAGMENTS CODING THIS ANTIBODY AND ANTIGEN-BINDING FRAGMENT | 2016 |
|
RU2644334C2 |
| MONOCLONAL ANTIBODY, BINDING WITH EBOLA VIRUS GLYCOPROTEIN, DNA FRAGMENTS CODING THIS ANTIBODY, AND ANTIGEN-BINDING FRAGMENT | 2015 |
|
RU2639533C2 |
| MONOCLONAL ANTIBODY, BINDING WITH EBOLA VIRUS GLYCOPROTEIN, DNA FRAGMENTS CODING THIS ANTIBODY, AND ANTIGEN-BINDING FRAGMENT | 2015 |
|
RU2630304C2 |
| HUMANISED ANTIBODY AND ANTIGENBINDING FRAGMENT (Fab), WHICH BINDS WITH HUMAN INTERFERON-γ, DNA FRAGMENTS CODING CLAIMED ANTIBODY AND ANTIGEN-BINDING FRAGMENT, CELL, TRANSFORMED BY DNA FRAGMENT, AND METHOD OF OBTAINING CLAIMED ANTIBODY AND ANTIGEN-BINDING FRAGMENT | 2013 |
|
RU2539752C2 |
| INTERFERON ALPHA 1 RECEPTOR ANTIBODIES AND USE THEREOF | 2005 |
|
RU2600884C2 |
| VARIABLE DOMAINS OF LIGHT AND HEAVY CHAIN OF MURINE MONOCLONAL ANTIBODY AGAINST TUMOUR NECROSIS FACTOR ALPHA (TNF-α) OF HUMAN BEING (VERSIONS); ANTIGEN-BINDING FRAGMENT (Fab) AGAINST TNF-α OF HUMAN BEING, WHICH CONTAINS ABOVE SAID DOMAINS (VERSIONS) | 2012 |
|
RU2499000C1 |
