ANTIVIRAL ACTIVITY OF FULLERENE AQUEOUS SOLUTION Russian patent published in 2019 - IPC C01B32/152 

Abstract RU 2694754 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to immunology, and can be used for treating herpes virus infections, where the antiviral agent used is an aqueous solution of fullerene dnC60. Antiviral activity in vitro of fullerene dnC60 solution studied on Vero culture. Experiments have shown that an aqueous solution of fullerene dnC60 shows manifested virucidal, preventive and therapeutic activity. A therapeutic effect in vivo is tested in a model of herpetic infection of mice. Treatment of animals with fullerene dnC60 solution statistically significant reduction of clinical manifestations of herpetic infection.

EFFECT: obtained results allow to conclude that the aqueous solution shows pronounced therapeutic activity against HSV-1 infection, wherein its therapeutic effect is comparable to the reference preparation ACV when used in 500 times less than the concentration.

4 cl, 6 dwg, 2 tbl, 5 ex

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RU 2 694 754 C1

Authors

Klimova Regina Rafailovna

Momotyuk Ekaterina Dmitrievna

Demidova Natalya Andreevna

Kushch Alla Aleksandrovna

Andreev Sergej Mikhajlovich

Turetskij Evgenij Aleksandrovich

Baraboshkina Elena Nikolaevna

Khaitov Musa Rakhimovich

Gintsburg Aleksandr Leonidovich

Shershakova Nadezhda Nikolaevna

Dates

2019-07-16Published

2018-10-16Filed