FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to immunology, and can be used for treating herpes virus infections, where the antiviral agent used is an aqueous solution of fullerene dnC60. Antiviral activity in vitro of fullerene dnC60 solution studied on Vero culture. Experiments have shown that an aqueous solution of fullerene dnC60 shows manifested virucidal, preventive and therapeutic activity. A therapeutic effect in vivo is tested in a model of herpetic infection of mice. Treatment of animals with fullerene dnC60 solution statistically significant reduction of clinical manifestations of herpetic infection.
EFFECT: obtained results allow to conclude that the aqueous solution shows pronounced therapeutic activity against HSV-1 infection, wherein its therapeutic effect is comparable to the reference preparation ACV when used in 500 times less than the concentration.
4 cl, 6 dwg, 2 tbl, 5 ex
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Authors
Dates
2019-07-16—Published
2018-10-16—Filed