FIELD: medicine.
SUBSTANCE: invention describes a method for preparing compositions containing tumour cell stress proteins, which involves the following steps: obtaining tumour cells in a culture medium; effect on tumour cells from stage 1) with stress so that these cells generate stress proteins in response to stress; obtaining or extracting stress cells and/or stress proteins; treatment of stressed tumour cells and/or obtained stress proteins by a molecule or a method capable of making stress proteins immunogenic, preferably hapten or by haptenilation method.
EFFECT: invention also describes pharmaceutical compositions containing tumour cell stress proteins and/or tumour cells containing stress proteins which have become immunogenic, particularly haptenilised, as well as a pharmaceutically acceptable excipient.
27 cl, 6 dwg, 6 ex
Authors
Dates
2019-07-16—Published
2014-10-15—Filed