THERAPEUTIC CANCER VACCINE BASED ON STRESS PROTEINS AS IMMUNOGENS Russian patent published in 2019 - IPC A61K38/17 A61K39/00 A61P35/00 

Abstract RU 2694761 C2

FIELD: medicine.

SUBSTANCE: invention describes a method for preparing compositions containing tumour cell stress proteins, which involves the following steps: obtaining tumour cells in a culture medium; effect on tumour cells from stage 1) with stress so that these cells generate stress proteins in response to stress; obtaining or extracting stress cells and/or stress proteins; treatment of stressed tumour cells and/or obtained stress proteins by a molecule or a method capable of making stress proteins immunogenic, preferably hapten or by haptenilation method.

EFFECT: invention also describes pharmaceutical compositions containing tumour cell stress proteins and/or tumour cells containing stress proteins which have become immunogenic, particularly haptenilised, as well as a pharmaceutically acceptable excipient.

27 cl, 6 dwg, 6 ex

Similar patents RU2694761C2

Title Year Author Number
METHOD OF STRENGTHENING CYTOTOXIC EFFECTS OF PANOBINOSTAT ON TUMOR CELLS 2023
  • Kabakov Aleksandr Evgenevich
  • Mosina Vera Alekseevna
  • Khokhlova Anna Viacheslavovna
  • Shegai Petr Viktorovich
  • Ivanov Sergei Anatolevich
  • Kaprin Andrei Dmitrievich
RU2806371C2
VACCINE COMPOSITIONS, METHODS FOR APPLICATION THEREOF IN MELANOMA PREVENTION AND TREATMENT, AND GENETIC CONSTRUCTIONS FOR OBTAINING ACTIVE SUBSTANCES OF COMPOSITION 2006
  • Digtjar' Anton Vasil'Evich
  • Lutsenko Elena Valer'Evna
  • Lutsenko Sergej Viktorovich
  • Pozdnjakova Natal'Ja Vladimirovna
  • Severin Evgenij Sergeevich
  • Severin Sergej Evgen'Evich
  • Solov'Ev Andrej Ivanovich
  • Fel'Dman Natalija Borisovna
  • Khomjakova Anastasija Viktorovna
RU2333767C2
USE OF LECTINS FOR GLYCOPROTEIDS AND ANTIGENIC MOLECULES OLIGOMERISATION ACTIVATION 2004
  • Zabreki Dzhejms R.
  • Monks Stefen A.
RU2399381C2
APPLICATION OF HEAT SHOCK PROTEINS FOR IMPROVEMENT OF THERAPEUTICAL EFFECT OF NON-VACCINAL MEDICINAL EFFECT 2003
  • Srivastava Pramod K.
  • Li Tszykhaj
RU2376029C2
APPLICATION OF HEAT-SHOCK PROTEINS FOR IMPROVING EFFECTIVENESS OF ANTIBODY THERAPIES 2003
  • Srivastava Pramod K.
RU2375077C2
USING HEAT SHOCK PROTEINS FOR IMPROVING THERAPEUTIC EFFECT OF NON-VACCINE THERAPEUTIC INTERVENTION 2009
  • Srivastava Pramod K
  • Li Tszykhaj
RU2573380C2
METHOD OF OBTAINING COMPOSITIONS INCLUDING HEAT SHOCK PROTEINS OR ALPHA-2-MACROGLOBULIN, SUITABLE FOR TREATMENT OF MALIGNANT TUMOUR AND INFECTIOUS DISEASE 2002
  • Srivastava Pramod K.
RU2335295C2
DIAGNOSING CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) 2009
  • Ankersmit Jan Khendrik
RU2549481C2
BIOMARKER FOR PATIENT SELECTION AND RELATED METHODS 2010
  • Brjus Akre
  • Benua Grell'E
RU2552292C2
VACCINE FOR ANTITUMOR IMMUNITY STIMULATION 2000
  • Seledtsov V.I.
  • Samarin D.M.
  • Seledtsova G.V.
  • Senjukov V.V.
  • Strunkin D.N.
  • Kozlov V.A.
RU2192884C2

RU 2 694 761 C2

Authors

Penter Benua

Devije Zhil

Dates

2019-07-16Published

2014-10-15Filed