FIELD: medicine.
SUBSTANCE: invention refers to medicine, particularly to a delayed-release oral cilostazol preparation. Preparation contains cilostazol as an active ingredient, hydroxypropyl methylcellulose as a hydrophilic polymer, carbomer as a delayed-release carrier and sodium lauryl sulphate as a solubilising agent.
EFFECT: oral preparation of cilostazol demonstrates a dissolution profile capable of effectively maintaining the drug concentration in the body, and an adequate initial dissolution rate, which enables to maintain the therapeutic effect of cilostazol even with a single daily intake, thereby reducing the occurrence of side effects and improving the compliance of the drug.
5 cl, 4 tbl, 9 ex, 2 dwg
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