FIELD: medicine; pharmacology.
SUBSTANCE: invention refers to medicine, namely to pharmacology, and concerns use of vegetable water-soluble polysaccharides with molecular weight of 1,070±50 and 17±2 kDa, extracted by means of the declared method from an elevated part of alfalfa (Medicago sativa L.), as an immunomodulatory agent for activation of antigen-presenting cells and selective stimulation of interleukin-12 production, tumor necrosis factor-alpha by macrophages and interferon-gamma lymphocytes.
EFFECT: invention enables extending the range of low-toxicity immunomodulatory agents for preventing and treating disorders of pathological conditions of the immune system in the therapy of chronic inflammatory diseases, including in paediatrics and gerontology, as well as in people with low reactivity of the immune system, characterized by high biological compatibility and biodegradability.
1 cl, 8 tbl, 3 ex
| Title |
Year |
Author |
Number |
| MEANS OF IMMUNOMODULATING ACTIVITY |
2017 |
- Danilets Marina Grigorevna
- Gurev Artem Mikhajlovich
- Trofimova Evgeniya Sergeevna
- Ligacheva Anastasiya Aleksandrovna
- Sherstoboev Evgenij Yurevich
- Belousov Mikhail Valerevich
- Yusubov Mekhman Sulejmanovich
- Tobolzhina Svetlana Aleksandrovna
- Rovkina Kseniya Igorevna
- Krivoshchekov Sergej Vladimirovich
|
RU2657819C1 |
| AGENT HAVING IMMUNOMODULATORY ACTIVITY |
2019 |
- Ligacheva Anastasiya Aleksandrovna
- Gurev Artem Mikhajlovich
- Danilets Marina Grigorevna
- Trofimova Evgeniya Sergeevna
- Sherstoboev Evgenij Yurevich
- Belousov Mikhail Valerevich
- Yusubov Mekhman Sulejmanovich
- Vidanova Irina Viktorovna
- Rovkina Kseniya Igorevna
- Krivoshchekov Sergej Vladimirovich
|
RU2734420C1 |
| IMMUNOMODULATORY DRUG |
2010 |
- Danilets Marina Grigor'Evna
- Gur'Ev Artem Mikhajlovich
- Bel'Skaja Natalija Vital'Evna
- Belousov Mikhail Valer'Evich
- Bel'Skij Jurij Pavlovich
- Jusubov Mekhman Sulejmanovich
- Trofimova Evgenija Sergeevna
- Agafonov Vladimir Ivanovich
- Uchasova Evgenija Gennad'Evna
- Ligacheva Anastasija Aleksandrovna
|
RU2421232C1 |
| IMMUNOMODULATORY DRUG |
2011 |
- Danilets Marina Grigor'Evna
- Ligacheva Anastasija Aleksandrovna
- Trofimova Evgenija Sergeevna
- Bel'Skaja Natalija Vital'Evna
- Bel'Skij Jurij Pavlovich
- Uchasova Evgenija Gennad'Evna
- Ivanova Alena Nikolaevna
- Agafonov Vladimir Ivanovich
- Churin Aleksej Aleksandrovich
- Gur'Ev Artem Mikhajlovich
- Belousov Mikhail Valer'Evich
- Jusubov Mekhman Sulejmanovich
|
RU2470656C1 |
| MEDICATION POSSESSING IMMUNOMODULATING ACTIVITY |
2010 |
- Danilets Marina Grigor'Evna
- Gur'Ev Artem Mikhajlovich
- Bel'Skaja Natalija Vital'Evna
- Belousov Mikhail Valer'Evich
- Bel'Skij Jurij Pavlovich
- Jusubov Mekhman Sulejmanovich
- Trofimova Evgenija Sergeevna
- Agafonov Vladimir Ivanovich
- Uchasova Evgenija Gennad'Evna
- Ligacheva Anastasija Aleksandrovna
|
RU2423141C1 |
| AGENT OF HUMIC NATURE OF IMMUNOMODULATING ACTIVITY |
2017 |
- Danilets Marina Grigorevna
- Zykova Mariya Vladimirovna
- Trofimova Evgeniya Sergeevna
- Ligacheva Anastasiya Aleksandrovna
- Sherstoboev Evgenij Yurevich
- Danilets Andrej Viktorovich
- Belousov Mikhail Valerevich
- Yusubov Mekhman Sulejmanovich
- Zhukova Kseniya Mikhajlovna
- Krivoshchekov Sergej Vladimirovich
- Logvinova Lyudmila Anatolevna
|
RU2662094C1 |
| HUMIC SUBSTANCE HAVING IMMUNOMODULATORY ACTIVITY |
2019 |
- Trofimova Evgeniya Sergeevna
- Zykova Mariya Vladimirovna
- Danilets Marina Grigorevna
- Ligacheva Anastasiya Aleksandrovna
- Sherstoboev Evgenij Yurevich
- Belousov Mikhail Valerevich
- Yusubov Mekhman Sulejmanovich
- Zhukova Kseniya Mikhajlovna
- Krivoshchekov Sergej Vladimirovich
- Logvinova Lyudmila Anatolevna
- Bratishko Kristina Aleksandrovna
|
RU2716504C1 |
| AGENT BASED ON WATER-SOLUBLE VEGETABLE POLYSACCHARIDES, HAVING ANTIALLERGIC ACTIVITY |
2023 |
- Danilets Marina Grigorevna
- Ligacheva Anastasiya Aleksandrovna
- Trofimova Evgeniya Sergeevna
- Sherstoboev Evgenij Yurevich
- Selivanova Natalya Sergeevna
- Avdeeva Elena Yurevna
- Belousov Mikhail Valerevich
- Reshetov Yaroslav Evgenevich
- Krivoshchekov Sergej Vladimirovich
- Gulina Ekaterina Igorevna
|
RU2823873C1 |
| AGENT BASED ON WATER-SOLUBLE PLANT POLYSACCHARIDES, ENHANCING NITRIC OXIDE SECRETION BY MACROPHAGES IN VITRO |
2018 |
- Danilets Marina Grigorevna
- Avdeeva Elena Yurevna
- Ligacheva Anastasiya Aleksandrovna
- Reshetov Yaroslav Evgenevich
- Gurev Artem Mikhajlovich
- Trofimova Evgeniya Sergeevna
- Sherstoboev Evgenij Yurevich
- Belousov Mikhail Valerevich
- Yusubov Mekhman Sulejmanovich
- Rovkina Kseniya Igorevna
- Krivoshchekov Sergej Vladimirovich
- Belskij Yurij Pavlovich
- Belskaya Natalya Vitalevna
|
RU2735080C2 |
| IMMUNOMODULATING HUMIC AGENT |
2020 |
|
RU2756353C1 |
