COMBINED PREPARATION OF MOSAPRIDE AND RABEPRAZOLE Russian patent published in 2019 - IPC A61K9/20 A61K9/48 A61K31/535 A61K31/416 A61K47/00 A61P1/00 

Abstract RU 2697836 C2

FIELD: pharmaceutics.

SUBSTANCE: group of inventions relates to the chemical-pharmaceutical industry and is a method for preparing a combined preparation and the combined preparation itself for treating, preventing, or relieving gastrointestinal disorders, or alleviating gastrointestinal symptoms, comprising: a first composition which contains mosapride or a pharmaceutically acceptable salt thereof as a first active ingredient, and a second composition which contains rabeprazole or a pharmaceutically acceptable salt thereof as a second active ingredient, wherein the combined preparation has a tablet structure with a core in which the second composition is contained as an inner core and the first composition surrounds the outer layer of the second composition.

EFFECT: group of inventions provides fast release of a drug from the preparation without disturbing its release by interaction between mosapride and rabeprazole, thus demonstrating an improved degree of drug release and bioavailability, wherein the preparation has excellent stability.

4 cl, 5 dwg, 9 tbl, 9 ex

Similar patents RU2697836C2

Title Year Author Number
COMBINED PHARMACEUTICAL WITH TABLET IN CORE, CONTAINING MOSAPRIDE AND RABEPRAZOLE 2018
  • Kim, Byung Jin
  • Song, Hee Yong
  • Choi, Youn Woong
  • Kim, Seong Yeob
RU2753697C1
MODIFIED RELEASE THERAPEUTIC SYSTEMS FOR ORAL ADMINISTRATION OF CURCUMIN IN TREATING INTESTINAL DISORDERS 2014
  • Pedrani Massimo
RU2692473C1
MODIFIED-RELEASE THERAPEUTIC SYSTEMS FOR ORAL ADMINISTRATION OF MENTHOL IN THE TREATMENT OF INTESTINAL DISORDERS 2014
  • Pedrani Massimo
RU2683645C1
DRUG COMPOSITIONS CONTAINING CONTROLLED RELEASE HYPROMELLOSE MATRIXES 2006
  • Radzhabi-Siakhboomi Ali
  • Fedzheli Kurt Alan
  • Joung Kara
  • Redzhe Pankadzh
RU2414241C2
PHARMACEUTICAL COMPOSITION FOR TREATMENT OF GASTRIC AND DUODENUM ULCER IN FORM OF SOLID GELATIN CAPSULES, WHICH CONTAINS RABEPRAZOLE OR ITS DERIVATIVES, AND METHOD OF ITS OBTAINING 2007
  • Shobolov Dmitrij L'Vovich
  • Papazova Natal'Ja Aleksandrovna
RU2414889C2
SOLID DOSAGE FORMS OF PALLBOCYCLOB 2016
  • Ibrahim Fady Makram Louiz
  • Mullarney Matthew Patrick
  • Shanker Ravi Mysore
  • Spong Barbara Rodriguez
  • Wang Jian
RU2686840C1
IMMEDIATE RELEASE COMPOSITIONS 2010
  • Kinter Kevin
  • Ramsey Peter
RU2541807C2
ANTIEMETIC EXTENDED RELEASE SOLID DOSAGE FORMS 2014
  • Fatkhi Reza
  • Radaj Gilead
RU2679448C2
PHARMACOLOGICAL COMPOSITION WITH SWELLING COATING 2004
  • Srinivas Irukulla
  • Diksit Akhilesh Ashok
  • Reddi Pallempalli Venkata Siva
  • Reddi Billa Pravin
  • Mokhan Mehjlatur Sivaraman
  • Ravinder Kodipjaka
  • Nasare Vidzhej
  • Pergament Ehduard
RU2375048C2
NEW CRYSTALLINE FORMS 2007
  • Oslund Bengt Leonard
  • Bengtsson Stefan
  • Bergman Gudrun Anita
  • Khol'Najkher Ursula Renata Marija
  • Imen Bo Ingvar
RU2446156C2

RU 2 697 836 C2

Authors

Choj Yun Vung

Son Khi En

Kha De-Chul

Kim Ben Dzhin

Dates

2019-08-21Published

2016-06-27Filed