METHOD FOR EARLY DIAGNOSIS OF LUNG CANCER Russian patent published in 2019 - IPC G16H50/20 A61B5/00 

Abstract RU 2697971 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely oncology, and can be used for screening of probability of lung cancer or detection of the given oncological disease at an early stage. Disclosed is a method comprising measuring the level of biomarkers in a biological fluid sample obtained from a subject: HE4, ApoA2, CYFRA.21.1, Ddimer, ApoA1, TTR, B2M, CA125, hsCRP, CEA, sVCAM.1, CA15.3, as well as determining a patient's sex with subsequent treatment of a set of derived values of biomarkers using at least one classification model trained to determine high or low probability of lung cancer.

EFFECT: invention provides higher accuracy of screening detection of the presence of cancer in a specific patient of the European population, and already at the early stages of its development by detecting and accounting for the original set of biomarkers based on the analysis of the serum or blood plasma fraction with accelerated diagnosed states.

4 cl, 10 dwg, 4 tbl, 1 ex

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RU 2 697 971 C1

Authors

Glybochko Petr Vitalevich

Svistunov Andrej Alekseevich

Fomin Viktor Viktorovich

Kopylov Filipp Yurevich

Sekacheva Marina Igorevna

Parshin Vladimir Dmitrievich

Gitel Evgenij Pavlovich

Ragimov Aligejdar Alekperovich

Poddubskaya Elena Vladimirovna

Dates

2019-08-21Published

2018-11-15Filed