FIELD: chemistry.
SUBSTANCE: invention relates to biochemistry, in particular to a pharmaceutical composition containing an isolated antibody or its antigen-binding fragment, which specifically binds to alpha-toxin (AT) S.aureus, and recovered antibody or its antigen-binding fragment, which specifically binds to antigen S.aureus, which is a surface determinant selected from a group consisting of IsdH and ClfA. Also disclosed is a method of treating an infection S.aureus using said composition, a method of reducing bacterial agglutination S.aureus using said composition.
EFFECT: invention has the ability effectively treat infections S.aureus.
9 cl, 11 ex, 7 tbl, 18 dwg
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Authors
Dates
2019-08-22—Published
2013-11-06—Filed