ANTIBODIES TO S. AUREUS SURFACE DETERMINANTS Russian patent published in 2019 - IPC C12P21/08 C07K16/12 A61K38/00 

Abstract RU 2698131 C2

FIELD: chemistry.

SUBSTANCE: invention relates to biochemistry, in particular to a pharmaceutical composition containing an isolated antibody or its antigen-binding fragment, which specifically binds to alpha-toxin (AT) S.aureus, and recovered antibody or its antigen-binding fragment, which specifically binds to antigen S.aureus, which is a surface determinant selected from a group consisting of IsdH and ClfA. Also disclosed is a method of treating an infection S.aureus using said composition, a method of reducing bacterial agglutination S.aureus using said composition.

EFFECT: invention has the ability effectively treat infections S.aureus.

9 cl, 11 ex, 7 tbl, 18 dwg

Similar patents RU2698131C2

Title Year Author Number
COMBINATIONS OF ANTIBODIES TO STAPHYLOCOCCUS AUREUS 2019
  • Tkaczyk, Christine
  • Sellman, Bret
  • Du, Qun
  • Damschroder, Melissa
  • Cohen, Taylor
RU2804815C2
ANTIBODIES AGAINST STAPHYLOCOCCUS AUREUS LEUKOTOXINS 2019
  • Tkaczyk, Christine
  • Sellman, Bret
  • Du, Qun
  • Damschroder, Melissa
  • Corti, Davide
  • Minola, Andrea
RU2805969C2
ANTIBODIES TO SURFACE DETERMINANTS OF S. AUREUS 2013
  • Sellman, Bret
  • Tkachik, Kristin
  • Chovdkhuri, Partkha, S.
  • Khua, Lej
  • Pavlik, Piter
  • Bojnpejn, Rebekka
  • Chan, Chev-Shun
RU2808018C2
STAPHYLOCOCCUS AUREUS CLUMPING FACTOR A (ClfA) ANTIBODY 2019
  • Tkaczyk, Christine
  • Sellman, Bret
  • Borrok Iii, Martin
  • Corti, Davide
  • Minola, Andrea
RU2818805C2
BISPECIFIC ANTIGEN-BINDING MOLECULES CONTAINING ANTI-FAP CLONE 212 2019
  • Bruenker Peter
  • Duerr Harald
  • Klein Christian
  • Umana Pablo
  • Bujotzek Alexander
  • Zielonka Joerg
  • Trumpfheller Christine
  • Rapp Moritz
  • Le Clech Marine
RU2799429C2
CD40 LIGAND THERAPEUTIC ANTIBODIES 2018
  • Lugovskoy, Alexey
RU2770209C2
BISPECIFIC ANTIBODIES TO CCL2 2020
  • Feng Shu
  • Fischer Jens
  • Gan Siok Wan
  • Georges Guy
  • Gertz Michael
  • Ho Wei Shiong Adrian
  • Jochner Anton
  • Jordan Gregor
  • Kettenberger Hubert
  • Lam Runyi Adeline
  • Majety Meher
  • Moelleken Joerg
  • Runza Valeria
  • Schaefer Martin
  • Schlothauer Tilman
  • Tiefenthaler Georg
  • Viert Maria
RU2819613C1
ADVANCED PROCOAGULANT ANTIBODIES 2019
  • Torn, Karina
  • Khansen, Byarne, Gram
  • Jonsen, Laust, Bruun
  • Kharndal, Mikkel, Nors
  • Yan, Chzhizhu
  • Estergaard, Khenrik
  • Grejzen, Per, Dzh
  • Jokhansson, Eva
  • Rash, Morten, Grenbekh
  • Chen, Tsziankhe
  • Svensson, Anders
  • Chzhu, Khajsun
  • Chzhou, Zhun
RU2810748C2
METHODS FOR DETECTING FOLATE RECEPTOR 1 IN PATIENT SAMPLE 2018
  • Syuj, Rejmond
  • Kalm-Merdek, Kerri
RU2759410C2
ANTIBODIES BINDING TO GPRC5D 2019
  • Fertig Georg
  • Klein Christian
  • Lorenz Stefan
  • Xu Wei
  • Bernasconi Marie-Luise
  • Bujotzek Alexander
RU2797268C2

RU 2 698 131 C2

Authors

Sellman Bret

Tkachik Kristin

Chovdkhuri Partkha S.

Khua Lej

Pavlik Piter

Bojnpejn Rebekka

Chan Chev-Shun

Dates

2019-08-22Published

2013-11-06Filed